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pentobarbital will minimize the extent or influence of cevimeline by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.
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Check Carefully (1)pentobarbital will minimize the extent or effect of hydrocodone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Caution when discontinuing CYP3A4 inducers which are coadministered with hydrocodone; plasma concentrations of hydrocodone may possibly raise and may lead to possibly deadly respiratory depressionSerious - Use Different (one)hydrocodone, pentobarbital.
pentobarbital will decrease the extent or impact of fruquintinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. If coadministration with reasonable CYP3A4 inducers is unavoidable, continue on to administer fruquintinib at recommended dosage.
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pentobarbital will reduce the level or result of etravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will minimize the level or influence of clozapine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will reduce the extent or outcome of paclitaxel protein bound by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unknown.
pentobarbital will minimize the level or outcome of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital get more info will lower the level or influence of fosamprenavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lower the extent or effect of lopinavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
Contraindicated (1)pentobarbital will reduce the extent or result of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with strong CYP3A4 inducers can result in lowered serum concentrations and lack of antimalarial efficacy